Gospel blues is a form of blues-based gospel music that has existed since the earliest days of the blues. It combines Christian, evangelistic lyrics with traditional blues instrumentation, most commonly featuring blues guitar accompaniment. The term 'holy blues' was originally coined to describe the music of Reverend Gary Davis, whose masterful traditional blues guitar playing was paired with deeply religious lyrics. 

Along with Blind Willie Johnson, Gary Davis is widely regarded as one of the genre's most influential and enduring performers. Other notable gospel blues artists include Sister Rosetta Tharpe and Washington Phillips.